Application of 2‐Dimensional Speckle Tracking Technology for Trastuzumab‐Induced Cardiotoxicity in a New Mouse Model

This study confirms that GLS, GRS, and GCS can predict early cardiac dysfunction in a mouse model using 2D-STE. Additionally, histological analysis further validated the overall nature of cardiac damage.

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Publication Details

Journal
Journal of Ultrasound in Medicine
Published
2025-06-28
DOI
https://doi.org/10.1002/jum.16755
Primary Topic
Chemotherapy-induced cardiotoxicity and mitigation
Type
article
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article

Application of 2‐Dimensional Speckle Tracking Technology for Trastuzumab‐Induced Cardiotoxicity in a New Mouse Model

Huaxing Zhang, Ruoling Han, Yingxuan Tu
Journal of Ultrasound in Medicine
Chemotherapy-induced cardiotoxicity and mitigation
article

Application of 2‐Dimensional Speckle Tracking Technology for Trastuzumab‐Induced Cardiotoxicity in a New Mouse Model

Huaxing Zhang, Ruoling Han, Yingxuan Tu
article en

Abstract

This study confirms that GLS, GRS, and GCS can predict early cardiac dysfunction in a mouse model using 2D-STE. Additionally, histological analysis further validated the overall nature of cardiac damage.

Journal of Ultrasound in MedicineVol. 44(11)
Hebei Medical University (CN), Fourth Hospital of Hebei Medical University (CN), Baoding People's Hospital (CN), Baoding No.1 Central Hospital
Good health and well-being
Openalex Percentile: Top 74%
Chemotherapy-induced cardiotoxicity and mitigation
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