ACK1 condensates promote STAT5 signaling in lung squamous cell carcinoma
Our findings highlight the crucial role of ACK1 condensates in oncogenic STAT5 signaling and suggest that targeting the formation of ACK1 condensates could serve as a potential therapeutic strategy for LUSC.
Authors
- Ruozheng Wei
- Jianming Pei (ORCID: https://orcid.org/0000-0001-9932-8206)
- Andong Liu (ORCID: https://orcid.org/0000-0003-3999-0657)
- Lu Xia (ORCID: https://orcid.org/0000-0002-5646-2648)
- Yanyang Song
Institutions
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-06-28
- DOI
- https://doi.org/10.1186/s12935-025-03862-3
- Citations
- 1
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hubei Province