Alterations in dynamic effective connectivity of brain functional networks in patients with high myopia: a Granger causality analysis
This study found that patients with high myopia exhibit significantly altered patterns of dEC, especially increased connectivity between the visual network, the DMN, and the limbic network. Furthermore, significantly increased intranetwork dEC within the visual network indicates enhanced internal visual information processing. These findings offer new insights into the neural mechanisms of high myopia and suggest that long-term visual impairment may trigger functional reorganization in both visual and nonvisual brain networks.
Authors
- Haoyu Yuan (ORCID: https://orcid.org/0000-0003-0087-8238)
- Lili Yao (ORCID: https://orcid.org/0000-0002-2988-1994)
- Zhizhong Dong (ORCID: https://orcid.org/0000-0002-4493-322X)
- Lin Zhou (ORCID: https://orcid.org/0009-0000-6006-9008)
- Hua Chai (ORCID: https://orcid.org/0009-0001-4113-027X)
- Xiaorong Wu (ORCID: https://orcid.org/0000-0003-4580-4304)
- Yang Duan (ORCID: https://orcid.org/0000-0003-4809-9516)
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
Publication Details
- Journal
- Neuroreport
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1097/wnr.0000000000002191
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China