The Missing Vein: A Case of Inferior Vena Cava Agenesis Presenting With Venous Thromboembolism

Agenesis of the inferior vena cava (IVC) is a rare congenital anomaly that is frequently identified incidentally in patients presenting with venous thromboembolism. The IVC is susceptible to a wide range of congenital anomalies. Due to its rarity and infrequent clinical encounters, it is often overlooked. We describe the case of a young man of African descent who presented with a deep vein thrombosis due to a previously unrecognized diagnosis of IVC agenesis. This case sheds light on IVC agenesis as an alternative diagnosis, especially in younger patients without traditional risk factors for venous thromboembolism.

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Journal
Cureus
Published
2025-06-27
DOI
https://doi.org/10.7759/cureus.86897
Primary Topic
Vascular anomalies and interventions
Type
article
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article

The Missing Vein: A Case of Inferior Vena Cava Agenesis Presenting With Venous Thromboembolism

Alok Iyer, Soraiya Manji, Zamanali Khakhar, Rajiv Patel et al.
Cureus
Vascular anomalies and interventions
article

The Missing Vein: A Case of Inferior Vena Cava Agenesis Presenting With Venous Thromboembolism

Alok Iyer, Soraiya Manji, Zamanali Khakhar, Rajiv Patel, William Carey, Sayed Ali, Antony Kimani
article en

Abstract

Agenesis of the inferior vena cava (IVC) is a rare congenital anomaly that is frequently identified incidentally in patients presenting with venous thromboembolism. The IVC is susceptible to a wide range of congenital anomalies. Due to its rarity and infrequent clinical encounters, it is often overlooked. We describe the case of a young man of African descent who presented with a deep vein thrombosis due to a previously unrecognized diagnosis of IVC agenesis. This case sheds light on IVC agenesis as an alternative diagnosis, especially in younger patients without traditional risk factors for venous thromboembolism.

CureusVol. 17(6)
University of Nairobi (KE), Aga Khan University Hospital Nairobi (KE), Aga Khan University Nairobi (KE)
Zero hunger
Openalex Percentile: Top 74%
Vascular anomalies and interventions
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