Low sensitivity of the fourth‐generation antigen/antibody HIV rapid diagnostic test Determine™ HIV Early Detect for detection of acute HIV infection at the point of care in rural Eswatini: a diagnostic accuracy study
The low sensitivity of Determine™ HIV Early Detect to detect AHI when performed at the point of care using finger-prick blood samples in our study contrasts with other published evaluations from laboratory settings and highlights the importance of field evaluations of the commonly used diagnostic tests.
Authors
- Roberto de la Tour
- Esther Mukooza (ORCID: https://orcid.org/0000-0002-8037-7873)
- Tom Ellman (ORCID: https://orcid.org/0000-0002-8743-8325)
- Sindy Matse
- Lenhle Dube
- Mpumelelo Mavimbela (ORCID: https://orcid.org/0000-0002-8056-3828)
- Bernhard Kerschberger (ORCID: https://orcid.org/0000-0003-0525-7262)
- Alexandra Calmy
- Nombuso Ntshalintshali
- Iza Ciglenečki (ORCID: https://orcid.org/0000-0003-0406-5218)
- Antonio Flores (ORCID: https://orcid.org/0000-0003-0677-9177)
- Nomvuyo Mabuza
- Melat Haile
- Sindisiwe Dlamini
- Olivia Keiser
- Skinner Lekelem
Institutions
- University of Geneva (CH)
- University Hospital of Geneva (CH)
- Médecins Sans Frontières (ZA)
- Médecins Sans Frontières (CH)
- Southern Africa Nazarene University (SZ)
- Ministry of Health (SZ)
Publication Details
- Journal
- Journal of the International AIDS Society
- Published
- 2025-06-28
- DOI
- https://doi.org/10.1002/jia2.26517
- Citations
- 3
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.11