A bedside-to-bench translational analysis of NF1 alterations and CDK4/6 inhibitor resistance in hormone receptor-positive metastatic breast cancer
Breast Cancer Research Foundation DRC-20-001, National Cancer Institute R01CA273246, National Institute of Health P30 CA142543, Susan G. Komen Breast Cancer Foundation SAB1800010, Department of Defence BC 210406, Mary Kay Ash Foundation International Postdoctoral Scholars in Cancer Research Fellowship.
Authors
- Arielle J. Medford (ORCID: https://orcid.org/0000-0002-0829-183X)
- Dan Ye (ORCID: https://orcid.org/0000-0001-7419-7748)
- Gerburg M. Wulf (ORCID: https://orcid.org/0000-0001-7868-6231)
- Ariella B. Hanker (ORCID: https://orcid.org/0000-0002-8655-8341)
- Todd C. Knepper (ORCID: https://orcid.org/0000-0001-7651-2406)
- Seth A. Wander (ORCID: https://orcid.org/0000-0002-4127-4708)
- Christine M. Walko (ORCID: https://orcid.org/0000-0001-8435-898X)
- Aditya Bardia (ORCID: https://orcid.org/0000-0003-4885-1157)
- Lianne Ryan
- Rosario Chica-Parrado
- Carlos L. Arteaga (ORCID: https://orcid.org/0000-0003-0870-9586)
- Jiemin Liao (ORCID: https://orcid.org/0000-0001-6848-5532)
- Leif William Ellisen (ORCID: https://orcid.org/0000-0003-0444-7910)
- Yasuaki Uemoto (ORCID: https://orcid.org/0000-0002-4862-3878)
- Hyo S. Han (ORCID: https://orcid.org/0000-0002-0072-0257)
- Maxwell R. Lloyd (ORCID: https://orcid.org/0000-0001-9810-0437)
- Emily Podany (ORCID: https://orcid.org/0000-0002-9700-3616)
- Nicole Zhang (ORCID: https://orcid.org/0009-0001-2706-5838)
- X. Cynthia
- Caroline Weipert (ORCID: https://orcid.org/0000-0002-0069-882X)
- Katherine Clifton (ORCID: https://orcid.org/0000-0001-8623-995X)
- Fabiana Napolitano (ORCID: https://orcid.org/0000-0002-2463-8952)
- Shiyuan Liu (ORCID: https://orcid.org/0000-0002-0470-7308)
- Chang‐Ching Lin (ORCID: https://orcid.org/0000-0001-6659-5543)
- Jennifer C Keenan
- Claire Wegrzyn
Institutions
- Beth Israel Deaconess Medical Center (US)
- Massachusetts College of Pharmacy and Health Sciences (US)
- Washington University in St. Louis (US)
- UCLA Health (US)
- Moffitt Cancer Center (US)
- Massachusetts General Hospital (US)
- Southwestern Medical Center (US)
- Guardant (United States) (US)
- Center for Cancer Research (US)
- UCLA Jonsson Comprehensive Cancer Center
- Harold C. Simmons Comprehensive Cancer Center
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- EBioMedicine
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1016/j.ebiom.2025.105828
- Citations
- 5
- Primary Topic
- Advanced Breast Cancer Therapies
- Type
- article
- Field-Weighted Citation Impact
- 7.59