Evaluation of oral and injectable liposome-based vaccines with synthesized lipid for Japanese encephalitis virus in Sprague-Dawley rats
The injectable formulation induced a stronger immune response; however, the oral formulation showed potential as an alternative. These findings suggest that refinement of the oral formulation may provide practical advantages such as ease of administration, non-invasiveness, and improved logistics. Such features could potentially contribute to broader immunization efforts, including those aimed at global disease control.
Authors
- Dong-Geun Lee (ORCID: https://orcid.org/0000-0003-4918-7593)
- Sang‐Hyeon Lee (ORCID: https://orcid.org/0000-0001-5427-9092)
- Heonwoo Lee (ORCID: https://orcid.org/0000-0002-9782-6014)
- Min Song
- Y. Xu
- Andre Kim (ORCID: https://orcid.org/0000-0002-0769-109X)
- Young Min Woo (ORCID: https://orcid.org/0000-0003-0235-1667)
- Keun Woo Lee
- I.D. Park
- Young Eui Jeong (ORCID: https://orcid.org/0000-0003-2065-301X)
- Ji Young Hyun
- J. Maitland Young
Institutions
- Silla University (KR)
- Korea Bio Polytechnic College (KR)
- Hansol Chemical (South Korea) (KR)
Publication Details
- Journal
- Clinical and Experimental Vaccine Research
- Published
- 2025-01-01
- DOI
- https://doi.org/10.7774/cevr.2025.14.e28
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of SMEs and Startups