Alterations of cerebral intrinsic activity in first-episode, drug-naive patients with major depressive disorder
This study demonstrates early-stage ALFF alterations in drug-naive MDD patients, particularly in brain regions implicated in cognitive and emotional regulation. These findings suggest potential neuroimaging biomarkers for the early diagnosis and intervention of MDD.
Authors
- Xiaoqi Huang (ORCID: https://orcid.org/0000-0001-8686-5010)
- Lianqing Zhang (ORCID: https://orcid.org/0000-0002-9338-6285)
- Shi Tang
- Qiyong Gong (ORCID: https://orcid.org/0000-0002-5912-4871)
- Xuan Bu
- Lu Lu (ORCID: https://orcid.org/0000-0002-4344-4096)
- Hailong Li (ORCID: https://orcid.org/0000-0003-0652-6655)
- Xinyu Hu (ORCID: https://orcid.org/0009-0009-7265-2730)
- Xiaoqi Hu
Institutions
- Sun Yat-sen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- BJPsych Open
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1192/bjo.2025.65
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00