Comparative outcomes of STEMI patients: Direct PCI-center admissions vs. transfers from non-PCI centers: NIS analysis, 2016-2021

Background: Timely transfer for PCI is crucial in managing STEMI, reducing myocardial damage, optimizing reperfusion therapy, and minimizing post-procedural complications. This study aimed to assess in-hospital outcomes of patients with STEMI transferred for PCI versus those directly admitted to PCI centers. Methods: The National Inpatient Sample (NIS) was analyzed for STEMI patients undergoing PCI between 2016-2021. Patients were categorized as primarily admitted or transferred based on transfer indicators. Logistic and linear regression models evaluated in-hospital mortality, length of stay, hospital charges, and post-procedure complications. Results: A weighted national estimate of 748,430 STEMI patients underwent PCI, with 625,520 directly admitted and 122,910 transferred. The mean patient age was 62 years, and 72% were male. Mortality rates did not significantly differ between groups. However, transferred patients had longer hospital stays (mean difference: 0.76 days, 95% CI: 0.68-0.85, P