A rare cause of obstructive hydrocephalus: Cerebral aspergillosis presenting as an intracranial space-occupying lesion in an immunocompetent adult

This case emphasizes the importance of early detection of unusual CA in immunocompetent individuals and the importance of combining surgical intervention with antifungal therapy. The patient presented with a rare form of CA as an intracranial mass causing obstructive hydrocephalus, which initially mimicked a tumor. Early diagnosis and effective management, including surgery and antifungal treatment with voriconazole, led to significant improvement despite incomplete mass removal. Multidisciplinary care and long-term monitoring are crucial for managing such complex cases.

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Publication Details

Journal
Surgical Neurology International
Published
2025-06-27
DOI
https://doi.org/10.25259/sni_997_2024
Primary Topic
Antifungal resistance and susceptibility
Type
article
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article

A rare cause of obstructive hydrocephalus: Cerebral aspergillosis presenting as an intracranial space-occupying lesion in an immunocompetent adult

James A. Balogun, Vanessa Martins, Festus Ayobami Oshunpidan, Olalekan Sherif Adebiyi et al.
1 links
Surgical Neurology International
Antifungal resistance and susceptibility
article

A rare cause of obstructive hydrocephalus: Cerebral aspergillosis presenting as an intracranial space-occupying lesion in an immunocompetent adult

James A. Balogun, Vanessa Martins, Festus Ayobami Oshunpidan, Olalekan Sherif Adebiyi, Adekunbi Omowumi Oshunpidan, Oluwatobi David Kunle-Ajagbe
article en

Abstract

This case emphasizes the importance of early detection of unusual CA in immunocompetent individuals and the importance of combining surgical intervention with antifungal therapy. The patient presented with a rare form of CA as an intracranial mass causing obstructive hydrocephalus, which initially mimicked a tumor. Early diagnosis and effective management, including surgery and antifungal treatment with voriconazole, led to significant improvement despite incomplete mass removal. Multidisciplinary care and long-term monitoring are crucial for managing such complex cases.

Surgical Neurology InternationalVol. 16
University College Hospital, Ibadan (NG), Lagos State University Teaching Hospital (NG), Olabisi Onabanjo University Teaching Hospital (NG)
Good health and well-being
Openalex Percentile: Top 81%
Antifungal resistance and susceptibility
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A rare cause of obstructive hydrocephalus: Cerebral aspergillosis presenting as an intracranial space-occupying lesion in an immunocompetent adult — James A. Balogun, Vanessa Martins, et al. · Surgical Neurology International (2025) | TGRS Research Map | TGRS