Transnasal transsphenoidal versus transcranial surgery for resection of sellar lesions; a national database analysis

We found that the TC approach to the sella was associated with higher rates of complications and greater mortality than the TNTS approach. The TC approach was also more likely to be performed in nonelective cases, but the difference in morbidity and mortality was driven by elective cases. Further study is warranted to identify lesion characteristics that may influence choice of approach and outcomes.