Clinical validation of antimicrobial dosing regimens for continuous renal replacement therapy based on an <i>ex vivo</i> dosing algorithm
These data support the use of ex vivo CRRT models to develop optimal dosing regimens for a variety of antimicrobials, which could then be validated in clinical trials.
Authors
- Marguerite L. Monogue (ORCID: https://orcid.org/0000-0001-8251-458X)
- Christina Koenig (ORCID: https://orcid.org/0000-0002-3354-3496)
- Hanna Roenfanz
- Joseph L. Kuti (ORCID: https://orcid.org/0000-0002-4464-3126)
- Yuwei Shen (ORCID: https://orcid.org/0009-0003-2542-386X)
- C McGrath
Institutions
- Hartford Hospital (US)
- Universität Hamburg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1093/jac/dkaf199
- Citations
- 2
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- U.S. Food and Drug Administration
- Food and Drug Administration