Cutaneous nontuberculous mycobacterial infection after intra-articular corticosteroid injection in a patient with psoriatic dactylitis

The incidence of skin nontuberculous mycobacterial (NTM) infections has been rising in recent years, paralleling the increase in invasive procedures and immunosuppression. We present a case involving a patient undergoing treatment with a tumor necrosis factor blocker (Etanercept®) for psoriatic dactylitis, who showed clinical deterioration 30 days following intra-articular corticosteroid therapy. Liquid culture media identified M. abscessus, prompting the initiation of combination antibiotic therapy. To the best of our knowledge, this is the first reported case of an NTM superinfection in dactylitis, underscoring the importance of screening for these infections in immunosuppressed patients receiving localized injectable treatments.

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Publication Details

Journal
Revista da Sociedade Brasileira de Medicina Tropical
Published
2025-01-01
DOI
https://doi.org/10.1590/0037-8682-0055-2025
Primary Topic
Mycobacterium research and diagnosis
Type
article
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article

Cutaneous nontuberculous mycobacterial infection after intra-articular corticosteroid injection in a patient with psoriatic dactylitis

Irene Francés Alexandre, Laísa Ezaguy de Hollanda, Guilherme Augusto Pivoto João, VERIADIANA RAMOS FERREIRA et al.
Revista da Sociedade Brasileira de Medicina Tropical
Mycobacterium research and diagnosis
article

Cutaneous nontuberculous mycobacterial infection after intra-articular corticosteroid injection in a patient with psoriatic dactylitis

Irene Francés Alexandre, Laísa Ezaguy de Hollanda, Guilherme Augusto Pivoto João, VERIADIANA RAMOS FERREIRA, Marcelo Cordeiro‐Santos, Mariana Santiago Bernardes, L.M. Santos, Daniela Vale Dias, CLERIA ANIZIA DA SILVA OLIVEIRA, Thais F.F. Magalhães, Rebeca de Oliveira Alves Melo Martins
article en

Abstract

The incidence of skin nontuberculous mycobacterial (NTM) infections has been rising in recent years, paralleling the increase in invasive procedures and immunosuppression. We present a case involving a patient undergoing treatment with a tumor necrosis factor blocker (Etanercept®) for psoriatic dactylitis, who showed clinical deterioration 30 days following intra-articular corticosteroid therapy. Liquid culture media identified M. abscessus, prompting the initiation of combination antibiotic therapy. To the best of our knowledge, this is the first reported case of an NTM superinfection in dactylitis, underscoring the importance of screening for these infections in immunosuppressed patients receiving localized injectable treatments.

Revista da Sociedade Brasileira de Medicina TropicalVol. 58
Fundação de Medicina Tropical (BR), Fundação Getulio Vargas (BR), Universidade Federal do Amazonas (BR)
Good health and well-being
Openalex Percentile: Top 78%
Mycobacterium research and diagnosis
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