External Validation of <scp>MRI</scp> ‐Based Prostate Cancer Risk Calculators in an Australian Cohort

Use of prostate biopsy decision-making tools provides avenues for individualized health care based on patient-specific risk factors. This study has successfully completed external validation of nine risk calculators, with one demonstrating adequate discriminatory capacity in all patients and three in biopsy-naïve patients. Systemic use may have a 12% net clinical benefit amongst biopsy-naïve patients, thereby reducing healthcare system burden.

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Publication Details

Journal
ANZ Journal of Surgery
Published
2025-06-27
DOI
https://doi.org/10.1111/ans.70211
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

External Validation of MRI ‐Based Prostate Cancer Risk Calculators in an Australian Cohort

Alex Jay, Sebastiaan Remmers, Kerry Santoro, Michael O’Callaghan et al.
ANZ Journal of Surgery
Prostate Cancer Diagnosis and Treatment
article

External Validation of MRI ‐Based Prostate Cancer Risk Calculators in an Australian Cohort

Alex Jay, Sebastiaan Remmers, Kerry Santoro, Michael O’Callaghan, Nicole A. Williams
article en

Abstract

Use of prostate biopsy decision-making tools provides avenues for individualized health care based on patient-specific risk factors. This study has successfully completed external validation of nine risk calculators, with one demonstrating adequate discriminatory capacity in all patients and three in biopsy-naïve patients. Systemic use may have a 12% net clinical benefit amongst biopsy-naïve patients, thereby reducing healthcare system burden.

ANZ Journal of SurgeryVol. 95(9)
Flinders Medical Centre (AU), Erasmus MC Cancer Institute (NL)
Reduced inequalities
Openalex Percentile: Top 75%
Prostate Cancer Diagnosis and Treatment
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