Glycyrrhiza uralensis Fisch. suppresses cell migration via ROS and JAK/STAT signalling pathways in Drosophila
Our findings demonstrate that GUF may serve as a promising candidate for targeting advanced metastatic tumors by suppressing ROS-mediated JAK/STAT signaling and EMT.
Authors
- Chenxi Wu (ORCID: https://orcid.org/0000-0003-2712-4823)
- Qingge Lu (ORCID: https://orcid.org/0000-0003-2372-1436)
- Haixia Zhang (ORCID: https://orcid.org/0000-0003-4194-2232)
- Lingyu Kong (ORCID: https://orcid.org/0000-0002-1216-2432)
- Fanwu Wu
- Meng Zhao (ORCID: https://orcid.org/0000-0003-0845-8270)
- Sitong Wang (ORCID: https://orcid.org/0000-0002-0531-7133)
- Yue Hu (ORCID: https://orcid.org/0000-0001-8679-5016)
- Fangfei Zhou
Institutions
- North China University of Science and Technology (CN)
- Tangshan People's Hospital (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- North China University of Science and Technology Affiliated Hospital (CN)
- Traditional Chinese Medicine Hospital of Kunshan (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-06-27
- DOI
- https://doi.org/10.3389/fphar.2025.1549920
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Westlake University
- Natural Science Foundation of Hebei Province