Long-term outcomes in patients with congenital adrenal hyperplasia treated with hydrocortisone modified-release hard capsules
Modified-release hard capsule treatment resulted in hydrocortisone dose reduction followed by a stable dose with improved biochemical control associated with fertility. Biochemical control could be reliably monitored by a single blood sample taken between 09:00 and 13:00 h. The incidence of adrenal crises was below that reported previously in patients with CAH.
Authors
- John Newell‐Price (ORCID: https://orcid.org/0000-0002-0835-5493)
- Wiebke Arlt (ORCID: https://orcid.org/0000-0001-5106-9719)
- Deborah P. Merke (ORCID: https://orcid.org/0000-0002-3746-0460)
- Angelica Lindén Hirschberg (ORCID: https://orcid.org/0000-0001-6481-6277)
- Hanna Bendfeldt
- Helen Coope
- Philippe Touraine (ORCID: https://orcid.org/0000-0002-8462-7753)
- Nicole Reisch (ORCID: https://orcid.org/0000-0002-7469-6069)
- Alessandro Prete (ORCID: https://orcid.org/0000-0002-4821-0336)
- Richard Ross (ORCID: https://orcid.org/0000-0001-9222-9678)
- Aled Rees (ORCID: https://orcid.org/0000-0002-1165-9092)
- Aude Brac de la Perrière (ORCID: https://orcid.org/0000-0001-6453-8326)
- John M. Porter (ORCID: https://orcid.org/0000-0002-1601-500X)
Institutions
- Karolinska University Hospital (SE)
- Karolinska Institutet (SE)
- Wikimedia UK (GB)
- LMU Klinikum (DE)
- Sorbonne Université (FR)
- Lille’s Cardiology Hospital (FR)
- Pitié-Salpêtrière Hospital (FR)
- Hôpital Louis Pradel (FR)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (US)
- National Institutes of Health Clinical Center (US)
- MRC London Institute of Medical Sciences (GB)
- NIHR Birmingham Biomedical Research Centre (GB)
- Imperial College London (GB)
- Cardiff University (GB)
- University of Birmingham (GB)
- Ludwig-Maximilians-Universität München (DE)
- University of Sheffield (GB)
Publication Details
- Journal
- European Journal of Endocrinology
- Published
- 2025-06-17
- DOI
- https://doi.org/10.1093/ejendo/lvaf130
- Citations
- 4
- Primary Topic
- Sexual Differentiation and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- National Institute for Health and Care Research
- Department of Health and Social Care
- National Institutes of Health
- Birmingham Biomedical Research Centre