Prostaglandin dose and time to fetal expulsion after intrauterine fetal death at 22 to 28 gestational weeks in Sweden: A retrospective cohort study

IUFD cases <28 GW induced with doses equivalent to misoprostol ≤200 μg within 6 h on average had significantly longer time to fetal expulsion and were almost twice as likely to have an induction >12 h compared to higher doses. Women with IUFD at this gestation would likely benefit from higher prostaglandin doses than those recommended in clinical guidelines if safety is ascertained.