Broadly reactive anti-VHH antibodies for characterizing, blocking, or activating nanobody-based CAR-T cells
Overall, these data identify useful anti-VHH mAbs that can be applied to better understand and manipulate VHH-based CAR-T cells or other VHH-based immunotherapies.
Authors
- Annie Fortin (ORCID: https://orcid.org/0009-0005-1532-6761)
- Andrea Acel
- Christine Gadoury
- Scott McComb (ORCID: https://orcid.org/0000-0002-4616-7864)
- Mathieu Coutu (ORCID: https://orcid.org/0009-0005-6624-810X)
- Marie Parat (ORCID: https://orcid.org/0000-0003-4835-4345)
- John K. Webb (ORCID: https://orcid.org/0000-0002-0004-9360)
- Tammy‐Lynn Tremblay
- Annie Aubry
- Félix Malenfant
- Jennifer J. Hill (ORCID: https://orcid.org/0000-0002-5550-8173)
- Bigitha Bennychen (ORCID: https://orcid.org/0000-0001-5779-2131)
- Simon Joubert (ORCID: https://orcid.org/0009-0007-0405-8946)
- Linda Lamoureux
- Anna N. Moraitis (ORCID: https://orcid.org/0000-0002-3416-480X)
- Sharlene Faulkes
- Aziza Manceur (ORCID: https://orcid.org/0000-0002-0148-9085)
- Joe Schrag
- Pierre Plante (ORCID: https://orcid.org/0000-0002-8790-4023)
- Shalini Raphael
- Joey Sheff (ORCID: https://orcid.org/0000-0002-9269-6863)
- Anne Marcil (ORCID: https://orcid.org/0000-0002-4111-1781)
- Martine Pagé (ORCID: https://orcid.org/0009-0000-0039-1935)
- Alex Shepherd
- Julie Lippens (ORCID: https://orcid.org/0000-0003-1147-0465)
- Mehdi Arbabi‐Ghahroudi
- Laura Tamblyn
- M. El Bakkouri
- Mauro Acchione (ORCID: https://orcid.org/0009-0001-5405-0068)
- Ahmed Zafer
- Greg Hussack (ORCID: https://orcid.org/0000-0002-9852-6865)
- Robert A. Pon
- Emma Smith (ORCID: https://orcid.org/0000-0001-7176-1868)
- Qin Zhu (ORCID: https://orcid.org/0000-0002-9472-8638)
- Bianca Dupont
- Tina Nguyen (ORCID: https://orcid.org/0009-0003-9942-7417)
- Risini D. Weeratna
- Cunle Wu
- Petra Pohankova
Institutions
- University of Ottawa (CA)
- National Academies of Sciences, Engineering, and Medicine (US)
- University of Victoria (CA)
- Institute for Systems Biology (US)
- Cancer Research Institute of the Slovak Academy of Sciences (SK)
- National Research Council Canada (CA)
- Institute of Infection and Immunity (CA)
Publication Details
- Journal
- Antibody Therapeutics
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1093/abt/tbaf011
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Council Canada