Evaluation of ceftazidime/avibactam in combination with colistin against KPC-2-producing <i>Klebsiella pneumoniae</i> in static and dynamic time-kill experiments
This study showed synergy with ceftazidime/avibactam and colistin against KPC-2-producing <i>K. pneumoniae</i> at clinically relevant concentrations. More studies are warranted to investigate the clinical potential of this combination.
Authors
- Lisa Allander
- Pernilla Lagerbäck
- Amaury O’Jeanson
- Linus Sandegren (ORCID: https://orcid.org/0000-0001-7382-9782)
- Thomas Tängdén (ORCID: https://orcid.org/0000-0001-7142-9849)
- Margarita Chatzopoulou
- Emma Vikdahl
Institutions
- Uppsala University (SE)
Publication Details
- Journal
- JAC-Antimicrobial Resistance
- Published
- 2025-04-29
- DOI
- https://doi.org/10.1093/jacamr/dlaf105
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Oxford Nanopore Technologies
- Institut National de la Santé et de la Recherche Médicale
- VINNOVA
- Vetenskapsrådet
- Akademiska Sjukhuset
- Uppsala Universitet
- Université de Poitiers