Persistent hypokalemia due to Conn’s syndrome resolved by robot-assisted laparoscopic adrenalectomy. A correct diagnostic approach for proper surgical therapy. Case report

Primary hyperaldosteronism, or Conn's syndrome, is a leading cause of secondary hypertension, often presenting with persistent hypokalemia. We report the case of a 44-year-old female with refractory hypokalemia and hypertension, ultimately diagnosed with a unilateral aldosterone-producing adenoma. Diagnostic workup included elevated transtubular potassium gradient and aldosterone-to-renin ratio, confirmed by computed tomography imaging showing a typical left adrenal adenoma. The patient underwent robot-assisted laparoscopic adrenalectomy, resulting in normalized potassium levels and discontinuation of antihypertensive medications. Histopathology confirmed adrenal adenoma. This case underscores the importance of a structured diagnostic algorithm in detecting surgically correctable causes of secondary hypertension. Robotic-assisted surgery offered superior precision, minimal blood loss, and rapid recovery, proving especially advantageous in complex or reoperative cases. In resource-limited settings, where advanced technology is scarce, promoting diagnostic accuracy is vital for effective management. This case advocates for the broader adoption of minimally invasive approaches and encourages investment in surgical innovation in developing countries.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-05-31
DOI
https://doi.org/10.1093/jscr/rjaf446
Primary Topic
Hormonal Regulation and Hypertension
Type
article
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article

Persistent hypokalemia due to Conn’s syndrome resolved by robot-assisted laparoscopic adrenalectomy. A correct diagnostic approach for proper surgical therapy. Case report

Fernando Stalin Jimenez Jaramillo, Santiago Muñoz-Palomeque, Damien Mosquera, Miguel R Mesías
Journal of Surgical Case Reports
Hormonal Regulation and Hypertension
article

Persistent hypokalemia due to Conn’s syndrome resolved by robot-assisted laparoscopic adrenalectomy. A correct diagnostic approach for proper surgical therapy. Case report

Fernando Stalin Jimenez Jaramillo, Santiago Muñoz-Palomeque, Damien Mosquera, Miguel R Mesías
article en

Abstract

Primary hyperaldosteronism, or Conn's syndrome, is a leading cause of secondary hypertension, often presenting with persistent hypokalemia. We report the case of a 44-year-old female with refractory hypokalemia and hypertension, ultimately diagnosed with a unilateral aldosterone-producing adenoma. Diagnostic workup included elevated transtubular potassium gradient and aldosterone-to-renin ratio, confirmed by computed tomography imaging showing a typical left adrenal adenoma. The patient underwent robot-assisted laparoscopic adrenalectomy, resulting in normalized potassium levels and discontinuation of antihypertensive medications. Histopathology confirmed adrenal adenoma. This case underscores the importance of a structured diagnostic algorithm in detecting surgically correctable causes of secondary hypertension. Robotic-assisted surgery offered superior precision, minimal blood loss, and rapid recovery, proving especially advantageous in complex or reoperative cases. In resource-limited settings, where advanced technology is scarce, promoting diagnostic accuracy is vital for effective management. This case advocates for the broader adoption of minimally invasive approaches and encourages investment in surgical innovation in developing countries.

Journal of Surgical Case ReportsVol. 2025(6)
Universidad Internacional del Ecuador (EC), Hospital Metropolitano (EC)
Industry, innovation and infrastructure
Openalex Percentile: Top 78%
Hormonal Regulation and Hypertension
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