Dissecting Morphological and Functional Dynamics of Non‐Tumorigenic and Triple‐Negative Breast Cancer Cell Lines Using <scp>PCA</scp> and t‐<scp>SNE</scp> Analysis
The profound differences in cellular dynamics between MCF10A and MDA-MB-231 cell lines underscore the unique adaptive mechanisms of TNBC cells. Our study provides valuable insights into the cellular foundations of TNBC aggressiveness, offering a foundation for future research aimed at understanding the mechanistic underpinnings of TNBC progression and therapeutic targeting.
Authors
- Besa Xhabija (ORCID: https://orcid.org/0000-0002-4784-2454)
- Yazan A. Almahdi
- Aidan J. McLaughlin
- Eva R. Schwark
Institutions
- University of Michigan–Dearborn (US)
Publication Details
- Journal
- Cancer Reports
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1002/cnr2.70257
- Citations
- 3
- Primary Topic
- Cell Image Analysis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 4.90
Funders
- University of Michigan-Dearborn