Adiponectin Receptor Agonist Suppresses Human Colorectal Cancer

AdipoRon effectively inhibited CRC cell proliferation and migration <i>in vitro</i>, effects that were associated with the up-regulation of the tumor suppressor protein pAMPKα and suppression of STAT3. These findings support the potential of AdipoRon as a promising therapeutic agent for CRC.

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Publication Details

Journal
Anticancer Research
Published
2025-06-27
DOI
https://doi.org/10.21873/anticanres.17670
Citations
1
Primary Topic
Adipokines, Inflammation, and Metabolic Diseases
Type
article
Field-Weighted Citation Impact
1.35
Controls
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article

Adiponectin Receptor Agonist Suppresses Human Colorectal Cancer

Khắc Cường Bùi, Przemyslaw Bozko, Christine Pham, Phuong Linh Thi Nham et al.
1 citations
Anticancer Research
Adipokines, Inflammation, and Metabolic Diseases
1.35
article

Adiponectin Receptor Agonist Suppresses Human Colorectal Cancer

Khắc Cường Bùi, Przemyslaw Bozko, Christine Pham, Phuong Linh Thi Nham, Lan Anh Bui, Văn Mão Cấn, T. D. Doan, Linh Toan Nguyen, Mai Ly Thi Nguyen
article en
1 citations

Abstract

AdipoRon effectively inhibited CRC cell proliferation and migration <i>in vitro</i>, effects that were associated with the up-regulation of the tumor suppressor protein pAMPKα and suppression of STAT3. These findings support the potential of AdipoRon as a promising therapeutic agent for CRC.

Anticancer ResearchVol. 45(7)
Universitätsklinikum Tübingen (DE), Universitätsmedizin Göttingen (DE), Vietnam Military Medical University (VN), German Centre for Cardiovascular Research (DE), 108 Military Central Hospital (VN)
Good health and well-being
Openalex Percentile: Top 18%
Adipokines, Inflammation, and Metabolic Diseases
1.35
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