ITGAV Regulation of LGALS3BP-JUNB Axis Facilitates the Cell-to-Cell Adhesion and Invasiveness of Hepatic Cancer Cells

The <i>LGALS3BP</i>-<i>JUNB</i> axis regulates <i>ITGAV</i> expression and contributes to HCC progression. Targeting <i>ITGAV</i>, with <i>LGALS3BP</i> as a potential biomarker, and the combined inhibition of both <i>LGALS3BP</i> and <i>ITGAV</i> may represent a promising therapeutic strategy for HCC.

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Publication Details

Journal
Anticancer Research
Published
2025-06-27
DOI
https://doi.org/10.21873/anticanres.17665
Primary Topic
Ubiquitin and proteasome pathways
Type
article
Field-Weighted Citation Impact
0.00
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article

ITGAV Regulation of LGALS3BP-JUNB Axis Facilitates the Cell-to-Cell Adhesion and Invasiveness of Hepatic Cancer Cells

Dae‐Hwan Kim, Sang‐Hee Cho, Ik‐Joo Chung, H.-J. Shim et al.
Anticancer Research
Ubiquitin and proteasome pathways
article

ITGAV Regulation of LGALS3BP-JUNB Axis Facilitates the Cell-to-Cell Adhesion and Invasiveness of Hepatic Cancer Cells

Dae‐Hwan Kim, Sang‐Hee Cho, Ik‐Joo Chung, H.-J. Shim, Min Seok Park, Woo‐Kyun Bae
article en

Abstract

The <i>LGALS3BP</i>-<i>JUNB</i> axis regulates <i>ITGAV</i> expression and contributes to HCC progression. Targeting <i>ITGAV</i>, with <i>LGALS3BP</i> as a potential biomarker, and the combined inhibition of both <i>LGALS3BP</i> and <i>ITGAV</i> may represent a promising therapeutic strategy for HCC.

Anticancer ResearchVol. 45(7)
Chonnam National University Hwasun Hospital (KR)
Openalex Percentile: Top 86%
Ubiquitin and proteasome pathways
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