Piperine Targets MAOB and Enhances Temozolomide-induced Cytotoxicity in Glioblastoma Cell Lines
Piperine exerts anti-GBM effects by targeting MAOB, disrupting ROS homeostasis, and inducing DNA damage. It also enhances TMZ efficacy, highlighting its potential as an adjuvant therapy for GBM.
Authors
- T.H. Kim
- D. G. Kim (ORCID: https://orcid.org/0000-0003-3706-2603)
- Chun Chul Shin
- Hye‐Mi Kim (ORCID: https://orcid.org/0000-0003-0337-9223)
Institutions
- Kyungpook National University (KR)
- Korea Institute of Radiological and Medical Sciences (KR)
- Daegu-Gyeongbuk Medical Innovation Foundation (KR)
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-06-27
- DOI
- https://doi.org/10.21873/anticanres.17666
- Primary Topic
- Piperaceae Chemical and Biological Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00