Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhance Cisplatin-induced Apoptotic Effects<i>via</i>the ROS-Fas Pathway in Human NPC-TW01 Nasopharyngeal Carcinoma Cells
hUC MSC-Exos enhance cisplatin-induced cytotoxicity in NPC-TW01 cells through ROS-dependent activation of the Fas-associated apoptotic signaling pathway. These results suggest that hUC MSC-Exos may serve as a promising adjuvant to augment the therapeutic efficacy of cisplatin in NPC.
Authors
- Chih-Chieh Tao (ORCID: https://orcid.org/0000-0001-8778-0449)
- Bu‐Miin Huang (ORCID: https://orcid.org/0000-0002-6966-832X)
- Y. Li
- Yu-Yan Lan (ORCID: https://orcid.org/0000-0003-4436-2057)
Institutions
- China Medical University (TW)
- China Medical University Hospital (TW)
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-06-27
- DOI
- https://doi.org/10.21873/anticanres.17675
- Citations
- 3
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 2.81