Low-dose Apalutamide in Non-metastatic Castration-resistant Prostate Cancer: A Case Series

Low-dose apalutamide was effective in this 6-patient case series. While awaiting new dose-response studies, we propose an apalutamide dose prescription flowchart that can be adapted for individual patients to avoid exposure to higher doses of the drug.

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Publication Details

Journal
Anticancer Research
Published
2025-06-27
DOI
https://doi.org/10.21873/anticanres.17676
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Low-dose Apalutamide in Non-metastatic Castration-resistant Prostate Cancer: A Case Series

Nguyen Minh Dung, Olena Gorobets, Claire F. Verschraegen, Vincent Vinh‐Hung et al.
Anticancer Research
Prostate Cancer Treatment and Research
article

Low-dose Apalutamide in Non-metastatic Castration-resistant Prostate Cancer: A Case Series

Nguyen Minh Dung, Olena Gorobets, Claire F. Verschraegen, Vincent Vinh‐Hung, Johan Rose Dite Modestine, YANNICK JOEL DJOUA
article en

Abstract

Low-dose apalutamide was effective in this 6-patient case series. While awaiting new dose-response studies, we propose an apalutamide dose prescription flowchart that can be adapted for individual patients to avoid exposure to higher doses of the drug.

Anticancer ResearchVol. 45(7)
Centre Hospitalier de Perpignan (FR), Centre Hospitalier Universitaire de Martinique (MQ), Centre Hospitalier Public du Cotentin (FR)
Bristol-Myers Squibb, Pfizer, AstraZeneca, Sanofi, MSD France, Ipsen, Cilag
Good health and well-being
Openalex Percentile: Top 75%
Prostate Cancer Treatment and Research
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