Bis-type Triaziquone Induces Apoptotic Effects in Human OEC-M1 Oral Cancer Cells
BTZQ effectively reduces the viability of OEC-M1 cells, showing greater toxicity to them compared to normal OF cells. It also induces several apoptotic features, including an increased subG1 phase population, PARP cleavage, and caspase activation in OEC-M1 cells, highlighting its potential as an oral cancer therapeutic by promoting apoptosis.
Authors
- Chih-Chun Wang (ORCID: https://orcid.org/0000-0002-1685-820X)
- Yuh‐Ling Lin
- Bu‐Miin Huang (ORCID: https://orcid.org/0000-0002-6966-832X)
- CHUNG-CHI HSU
- Yu-Yan Lan (ORCID: https://orcid.org/0000-0003-4436-2057)
- Tao Chen (ORCID: https://orcid.org/0000-0002-8371-779X)
- Yihang Wu (ORCID: https://orcid.org/0000-0003-4862-7243)
Institutions
- China Medical University (TW)
- China Medical University Hospital (TW)
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-06-27
- DOI
- https://doi.org/10.21873/anticanres.17671
- Primary Topic
- Electron Spin Resonance Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00