Anti-cancer Effects of a Novel Curcumin Derivative, 4,4-Diallyl Curcumin Bis(2,2-Hydroxymethyl)Propanoate (35e), on Radio-resistant Colorectal Cancer Cells
35e effectively inhibits growth and induces apoptosis in radio-resistant colorectal cancer cells by targeting multiple signaling pathways. These findings suggest that 35e is a promising therapeutic candidate for overcoming radio-resistance in colorectal cancer.
Authors
- Ching-Wen Huang
- Yeh‐Chun Juan (ORCID: https://orcid.org/0000-0002-3956-7093)
- Chung-Hua Hsu (ORCID: https://orcid.org/0000-0002-2496-7246)
- Yu‐Jen Chiu (ORCID: https://orcid.org/0000-0002-8065-0876)
- Yuh‐Feng Tsai
- Jai‐Sing Yang (ORCID: https://orcid.org/0000-0001-7302-8248)
- Sheng-Chu Kuo
- Meng-Wei Lin
Institutions
- National Yang Ming Chiao Tung University (TW)
- China Medical University (TW)
- China Medical University Hospital (TW)
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-06-27
- DOI
- https://doi.org/10.21873/anticanres.17657
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00