The impact of magnitude and duration of plasma viremia during analytical treatment interruptions on CD4+ T cell recovery after ART resumption

In our pooled analysis, high peak rebound pVLs and longer duration of viremia did not impair CD4<sup>+</sup> T cell recovery following the resumption of ART, supporting the safety of more flexible ATIs in HIV-1 cure trials.

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Publication Details

Journal
Journal of Virus Eradication
Published
2025-06-27
DOI
https://doi.org/10.1016/j.jve.2025.100604
Primary Topic
HIV Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

The impact of magnitude and duration of plasma viremia during analytical treatment interruptions on CD4+ T cell recovery after ART resumption

Ole S. Søgaard, Vibeke Klastrup, Jesper Damsgaard Gunst
Journal of Virus Eradication
HIV Research and Treatment
article

The impact of magnitude and duration of plasma viremia during analytical treatment interruptions on CD4+ T cell recovery after ART resumption

Ole S. Søgaard, Vibeke Klastrup, Jesper Damsgaard Gunst
article en

Abstract

In our pooled analysis, high peak rebound pVLs and longer duration of viremia did not impair CD4<sup>+</sup> T cell recovery following the resumption of ART, supporting the safety of more flexible ATIs in HIV-1 cure trials.

Journal of Virus EradicationVol. 11(3)
Aarhus University (DK), Aarhus University Hospital (DK)
Aarhus Universitet, Lundbeckfonden, Danmarks Frie Forskningsfond, Health Research Fund of Central Denmark Region
Good health and well-being
Openalex Percentile: Top 84%
HIV Research and Treatment
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