Therapeutic Potential of Chinese Edible Frog (Hoplobatrachuschinensis) Powdered Skin for Enhanced Wound epithelialization and Rapid Wound Recovery

Wound healing is a complex process crucial for tissue restoration and functionality.Despite advancements in medical field, challenges persist with the use of conventional approaches in wound healing, particularly with antibiotic resistance pathogen.This study investigated the presence of bioactive compounds, particularly peptides, in Hoplobatrachuschinensis frog skin.A Color test using Ninhydrin and Biuret was conducted which confirmed the presence of peptides in the powdered frog skin, indicating the skin's potential therapeutic properties.The study further examined the effect of different concentrations of powdered frog skin on wound contraction rate, epithelialization time, and overall healing.Statistical analysis showed that the skin of H.chinensis accelerated the wound recovery time, wound epithelialization and increases wound contraction rate.Results revealed that higher concentrations of powdered frog skin led to faster wound contraction and epithelialization, as well as shorter overall healing times.In conclusion, Hoplobatrachuschinensis skin contained bioactive compounds that can promote wound healing, with higher concentrations of powdered frog skin shows superior therapeutic effects.These findings suggest that powdered frog skin could serve as a promising natural alternative for wound management.