Amentoflavone Enhances the Anti-tumor Activity of Regorafenib by Promoting Apoptosis and Inhibiting NF-κB–mediated Metastasis in Hepatocellular Carcinoma

Amentoflavone potentiates regorafenib's anti-tumor effects in HCC by promoting apoptosis and blocking NF-κB-mediated metastatic signaling, supporting its use as a safe and effective adjuvant strategy.

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Publication Details

Journal
Anticancer Research
Published
2025-06-27
DOI
https://doi.org/10.21873/anticanres.17669
Citations
3
Primary Topic
Biological Activity of Diterpenoids and Biflavonoids
Type
article
Field-Weighted Citation Impact
2.42
Controls
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article

Amentoflavone Enhances the Anti-tumor Activity of Regorafenib by Promoting Apoptosis and Inhibiting NF-κB–mediated Metastasis in Hepatocellular Carcinoma

Fei‐Ting Hsu, Chia‐Jung Tsai, Rong‐Fong Lin, KUANG-HSUAN LIN et al.
3 citations
Anticancer Research
Biological Activity of Diterpenoids and Biflavonoids
2.42
article

Amentoflavone Enhances the Anti-tumor Activity of Regorafenib by Promoting Apoptosis and Inhibiting NF-κB–mediated Metastasis in Hepatocellular Carcinoma

Fei‐Ting Hsu, Chia‐Jung Tsai, Rong‐Fong Lin, KUANG-HSUAN LIN, Ying‐Tzu Chen, Yu‐Cheng Kuo, Cheng‐Tau Su
article en
3 citations

Abstract

Amentoflavone potentiates regorafenib's anti-tumor effects in HCC by promoting apoptosis and blocking NF-κB-mediated metastatic signaling, supporting its use as a safe and effective adjuvant strategy.

Anticancer ResearchVol. 45(7)
Ministry of Health and Welfare (KR), National Yang Ming Chiao Tung University (TW), Kaohsiung Medical University (TW), China Medical University (TW), National Central University (TW), Chang Bing Show Chwan Memorial Hospital (TW), China Medical University Hospital (TW), Central Taiwan University of Science and Technology (TW), I-Shou University (TW)
Good health and well-being
Openalex Percentile: Top 11%
Biological Activity of Diterpenoids and Biflavonoids
2.42
DOIOpen Access PDFOpenAlex
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Amentoflavone Enhances the Anti-tumor Activity of Regorafenib by Promoting Apoptosis and Inhibiting NF-κB–mediated Metastasis in Hepatocellular Carcinoma — Fei‐Ting Hsu, Chia‐Jung Tsai, et al. · Anticancer Research (2025) | TGRS Research Map | TGRS