Antitumor Effects of Epigallocatechin-3-Gallate on Colorectal Cancer: An<i>In Vitro</i>and<i>In Vivo</i>Study
EGCG suppresses the proliferation of human colon cancer cells through induction of apoptosis. Down-regulation of hsa-miR-187-5p may be a potential marker for the effect of EGCG in regulating colorectal cancer. These findings suggest that EGCG may serve as a promising therapeutic agent or adjunct in the treatment of colorectal cancer.
Authors
- Tatsuo Yachida (ORCID: https://orcid.org/0000-0003-2564-9781)
- Tomoko Tadokoro (ORCID: https://orcid.org/0000-0001-9975-386X)
- Hideki Kobara (ORCID: https://orcid.org/0000-0002-8508-827X)
- Akihiro Kitaoka
- M. Nakahara (ORCID: https://orcid.org/0000-0002-3227-0801)
- Joji Tani (ORCID: https://orcid.org/0000-0001-8801-2505)
- SHINTARO FUJIHARA
- Tsutomu Masaki (ORCID: https://orcid.org/0000-0002-8425-0685)
- Fumiyuki Suetsugu
- Takanori Matsui (ORCID: https://orcid.org/0000-0002-2517-1258)
- Koichi Nakatani
- Kazuhito Sasaki (ORCID: https://orcid.org/0000-0003-3569-6944)
- Kazuhiro Kozuka (ORCID: https://orcid.org/0000-0003-1763-7086)
- Koji Fujita (ORCID: https://orcid.org/0000-0001-9390-7565)
- Kyoko Oura (ORCID: https://orcid.org/0000-0002-9531-7240)
- ASAHIRO MORISHITA
- Yukiko Koyama
- Erika Omayu
Institutions
- Kagawa University (JP)
- Kagawa University Hospital (JP)
Publication Details
- Journal
- Anticancer Research
- Published
- 2025-06-27
- DOI
- https://doi.org/10.21873/anticanres.17661
- Citations
- 3
- Primary Topic
- Tea Polyphenols and Effects
- Type
- article
- Field-Weighted Citation Impact
- 4.41