Temporal Trends of Anticholinergic Drug Exposure Among Older Adults: A 25-Year Population-Based Study
Exposure to anticholinergic drugs has decreased by over 50% between 1996 and 2020 in this population of community-dwelling adults. However, the oldest old had and remained to have the highest risk of a cACB ≥ 3 during our study period. Thus, prescribers and pharmacists should continue to regularly review the prescription of drugs with an ACB, especially among those vulnerable to adverse outcomes.
Authors
- Bruno H. Stricker
- Silvan Licher (ORCID: https://orcid.org/0000-0002-4586-4035)
- Loes E. Visser (ORCID: https://orcid.org/0000-0002-1421-6246)
- Amanda Evelo
- Rikje Ruiter (ORCID: https://orcid.org/0000-0002-8107-2924)
Institutions
- Erasmus MC (NL)
- Maasstad Ziekenhuis (NL)
- Haga Hospital (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Drug Safety
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1007/s40264-025-01562-5
- Citations
- 2
- Primary Topic
- Pharmaceutical Practices and Patient Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.45
Funders
- European Commission
- ZonMw
- Erasmus Universiteit Rotterdam
- Ministerie van Volksgezondheid, Welzijn en Sport
- Erasmus Medisch Centrum
- Ministerie van Onderwijs, Cultuur en Wetenschap