MID-LLM: Enhancing Medical Image Diagnostics With LLMs in a Blockchain AI Framework

The rapid growth of medical imaging data presents significant challenges in diagnostic accuracy, data privacy, and computational efficiency. Traditional centralized AI models struggle with scalability and pose risks to patient confidentiality due to data aggregation. Moreover, heterogeneous medical data across institutions complicates the development of robust diagnostic tools. To address these issues, we propose MID-LLM, a novel framework that integrates Large Language Models (LLMs) with a blockchain-based federated learning system for medical image analysis. It also ensures the security and privacy of sensitive medical data across decentralized networks. MID-LLM uses verification mechanisms to ensure the global model’s integrity. It also employs aggregation techniques to reduce bias and improve training efficiency. Experiments on the BraTS 2020 dataset show that MID-LLM outperforms traditional federated learning, achieving higher Dice scores with improved computational efficiency. These results highlight MID-LLM’s potential to enhance diagnostic accuracy while offering a scalable, secure solution for AI in healthcare.