Prevalence, pathogenic bacteria, and risk factors associated with pediatric sepsis among under five children in a rural district hospital in Rwanda

The study reveals a high prevalence of sepsis among children under-five, especially females and less than 6 months with female gender and diagnosis with leukocytosis being a significant risk factor. Diagnostic strategies should focus on WBC counts to better manage at-risk children. These single-center study results however may not be broadly representative due to regional and resource differences, but they offer valuable insights for improving pediatric care in similar low-resource settings.

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Publication Details

Journal
PLoS ONE
Published
2025-06-27
DOI
https://doi.org/10.1371/journal.pone.0327425
Primary Topic
Neonatal and Maternal Infections
Type
article
Field-Weighted Citation Impact
0.00
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article

Prevalence, pathogenic bacteria, and risk factors associated with pediatric sepsis among under five children in a rural district hospital in Rwanda

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PLoS ONE
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article

Prevalence, pathogenic bacteria, and risk factors associated with pediatric sepsis among under five children in a rural district hospital in Rwanda

Louis Mujyuwisha, Jean Baptiste Niyibizi, Ezechiel Bizimana, Abebe Bekele, Patrick Orikiriza, David Ayebare, Deogratius Ruhangaza, Irene Nshimiyimana
article en

Abstract

The study reveals a high prevalence of sepsis among children under-five, especially females and less than 6 months with female gender and diagnosis with leukocytosis being a significant risk factor. Diagnostic strategies should focus on WBC counts to better manage at-risk children. These single-center study results however may not be broadly representative due to regional and resource differences, but they offer valuable insights for improving pediatric care in similar low-resource settings.

PLoS ONEVol. 20(6)
Partners In Health (US), Mbarara University of Science and Technology (UG), University of Global Health Equity (RW), University Teaching Hospital of Butare (RW)
Openalex Percentile: Top 79%
Neonatal and Maternal Infections
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