Efficacy of horizontal platelet‐rich fibrin on gingival tissue regeneration: Cellular and histological analysis

Horizontal platelet-rich fibrin (H-PRF) is a platelet concentrate derived from patient's own blood that has gained momentum in regenerative medicine due to its ability to support tissue repair. In our study, we compared the healing process of gingival defects treated with H-PRF to those that healed naturally and found that the defects treated with H-PRF healed more quickly and more completely. The treated areas contained stronger and more organized tissue, with improved blood flow. H-PRF also helps the cells in the gums move to the injury site more effectively, which is important for faster and more complete healing. Our findings suggest that H-PRF could be a useful tool to enhance the outcomes of soft tissue augmentation around natural teeth or implants, which would lead to healthier and stronger gingiva for patients.