Prolonged symptom duration and the potential for gradual progression in pediatric adrenocortical tumors: observations from the MET studies
A small subset of pACTs may present with prolonged endocrine symptoms, possibly reflecting gradual tumor evolution. While molecular validation is lacking, these findings support the need for early recognition and further research into the natural history of pACTs.
Authors
- Antje Redlich (ORCID: https://orcid.org/0000-0002-1732-1869)
- Michaela Kuhlen (ORCID: https://orcid.org/0000-0003-4577-0503)
- Michaela F. Hartmann (ORCID: https://orcid.org/0000-0001-7232-9532)
- Marina Kunstreich (ORCID: https://orcid.org/0000-0002-2672-4045)
- Rainer Claus (ORCID: https://orcid.org/0000-0003-2617-8766)
- Stefan Alexander Wudy (ORCID: https://orcid.org/0000-0002-7163-5957)
- Christian Vokuhl (ORCID: https://orcid.org/0000-0002-4138-4536)
- Clara Baumann
Institutions
- University of Bonn (DE)
- University of Augsburg (DE)
- Justus-Liebig-Universität Gießen (DE)
- Medizinische Hochschule Hannover (DE)
- Otto-von-Guericke-Universität Magdeburg (DE)
Publication Details
- Journal
- Journal of Pediatric Endocrinology and Metabolism
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1515/jpem-2025-0198
- Primary Topic
- Adrenal and Paraganglionic Tumors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Kinderkrebsstiftung