More Severe Brain Network Hierarchy Disorganization in Treatment-Naive Deficit Compared to Non-deficit Schizophrenia and Underlying Neurotransmitter Associations
The study suggests that independent from the potential effects of antipsychotic medication, DS and NDS are characterized by different neuropathology in brain hierarchy patterns, potentially linked to neurochemical metabolic distinction. Our findings support the hypothesis that DS is a distinct subtype versus NDS from neurodevelopmental perspective.
Authors
- Su Lui (ORCID: https://orcid.org/0000-0003-3541-1769)
- Jeffrey R. Bishop (ORCID: https://orcid.org/0000-0001-7653-8980)
- Qiyong Gong (ORCID: https://orcid.org/0000-0002-5912-4871)
- Lusi Zhang (ORCID: https://orcid.org/0000-0003-3716-9021)
- Zhipeng Yang (ORCID: https://orcid.org/0000-0002-2690-509X)
- Siyi Li (ORCID: https://orcid.org/0000-0002-6453-3979)
- Li Yao (ORCID: https://orcid.org/0000-0001-7730-7850)
- Jiajun Liu (ORCID: https://orcid.org/0009-0001-3677-613X)
- Wei Deng (ORCID: https://orcid.org/0000-0001-5937-9877)
- Chengmin Yang
- Kun Li (ORCID: https://orcid.org/0009-0005-1519-6303)
Institutions
- University of Minnesota (US)
- Xiamen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Sichuan University (CN)
- Chengdu University of Information Technology (CN)
- West China Hospital of Sichuan University (CN)
- Zhejiang Lab (CN)
- Hangzhou Seventh Peoples Hospital (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Schizophrenia Bulletin
- Published
- 2024-12-28
- DOI
- https://doi.org/10.1093/schbul/sbae231
- Citations
- 2
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.69
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities
- West China Hospital, Sichuan University