Treatment of Hypothyroidism That Contains Liothyronine is Associated With Reduced Risk of Dementia and Mortality
Despite standard LT4 therapy, hypothyroidism remains associated with heightened risks of dementia and mortality. Adding T3 may more effectively mitigate these risks than LT4 alone, but further studies are needed to confirm the cognitive and survival benefits of T3-containing regimens.
Authors
- George Golovko (ORCID: https://orcid.org/0000-0003-4609-2767)
- Matthew D Ettleson (ORCID: https://orcid.org/0000-0003-0328-1752)
- Antônio C. Bianco (ORCID: https://orcid.org/0000-0001-7737-6813)
- Fabyan Esberard de Lima Beltrão (ORCID: https://orcid.org/0000-0001-9713-2584)
- Helton Estrela Ramos (ORCID: https://orcid.org/0000-0002-2900-2099)
- Fabyo Napoleão de Lima Beltrão (ORCID: https://orcid.org/0000-0001-8796-2859)
- Miriam O. Ribeiro (ORCID: https://orcid.org/0000-0001-8637-676X)
- Vandrize Meneghini (ORCID: https://orcid.org/0000-0002-2787-6841)
- Giulia Carvalhal (ORCID: https://orcid.org/0000-0003-3386-5855)
- Daniele Carvalhal de Almeida Beltrão (ORCID: https://orcid.org/0000-0001-7187-5259)
- D. A. R. Matos (ORCID: https://orcid.org/0000-0001-7156-1532)
- Beatriz Bandeira de Andrade
Institutions
- Universidade Federal da Bahia (BR)
- Instituto Federal da Bahia (BR)
- Universidade Federal da Paraíba (BR)
- Universidade de São Paulo (BR)
- Universidade Presbiteriana Mackenzie (BR)
- University of Chicago (US)
- Universidade Federal de Campina Grande (BR)
- Departamento de Epidemiología (GT)
- Hospital Universitário Lauro Wanderley (BR)
- Centro Universitário de João Pessoa (BR)
- The University of Texas Medical Branch at Galveston (US)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-06-20
- DOI
- https://doi.org/10.1210/clinem/dgaf367
- Citations
- 3
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.88