Vitamin B6 challenge as a tool for detecting ALPL mutations and diagnosing hypophosphatasia
A 2-day vitamin B6 supplementation test may be useful for identifying carriers of ALPL mutations among individuals with unexplained low serum ALP.
Authors
- Antonio Ocampo (ORCID: https://orcid.org/0000-0002-3176-9758)
- S Sanchez Alvarez
- Leyre Riancho‐Zarrabeitia (ORCID: https://orcid.org/0000-0001-7642-0093)
- Ana Vega (ORCID: https://orcid.org/0000-0002-7416-5137)
- Nuria Puente (ORCID: https://orcid.org/0000-0001-9538-9917)
- Álvaro del Real (ORCID: https://orcid.org/0000-0002-1057-461X)
- José A. Riancho (ORCID: https://orcid.org/0000-0003-0691-8755)
- Maria Teresa Garcı́a-Unzueta (ORCID: https://orcid.org/0000-0003-2531-3284)
- Pio Caso
Institutions
- Universidad de Cantabria (ES)
- Marqués de Valdecilla University Hospital (ES)
- Hospital Sierrallana (ES)
- Centre for Biomedical Network Research on Rare Diseases (ES)
- Instituto de Investigación Marqués de Valdecilla (ES)
- Centro de Investigación Biomédica en Red (ES)
Publication Details
- Journal
- Osteoporosis International
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1007/s00198-025-07595-x
- Citations
- 1
- Primary Topic
- Alkaline Phosphatase Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- Universidad de Cantabria