Risk factors and predictive modeling of exclusive breastfeeding failure in mothers separated from their infants

This study explored factors contributing to exclusive breastfeeding failure in mothers separated from their infants and developed a predictive nomogram model. Clinical data from 258 such mothers admitted to the First Affiliated Hospital of Soochow University between June 2023 and June 2024 were analyzed. Among them, 119 experienced breastfeeding failure. Prolonged separation, lack of breastfeeding knowledge, inverted nipples, maternal anxiety, and depression were identified as independent risk factors. The nomogram model showed good predictive performance, with an AUC of 0.739 and positive net benefit across a wide range of threshold probabilities. This model could support targeted interventions in clinical practice.

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Publication Details

Journal
African Journal of Reproductive Health
Published
2025-06-27
DOI
https://doi.org/10.29063/ajrh2025/v29i6.3
Primary Topic
Breastfeeding Practices and Influences
Type
article
Field-Weighted Citation Impact
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article

Risk factors and predictive modeling of exclusive breastfeeding failure in mothers separated from their infants

Xiangxue Wang, Weiwei Wu
African Journal of Reproductive Health
Breastfeeding Practices and Influences
article

Risk factors and predictive modeling of exclusive breastfeeding failure in mothers separated from their infants

Xiangxue Wang, Weiwei Wu
article en

Abstract

This study explored factors contributing to exclusive breastfeeding failure in mothers separated from their infants and developed a predictive nomogram model. Clinical data from 258 such mothers admitted to the First Affiliated Hospital of Soochow University between June 2023 and June 2024 were analyzed. Among them, 119 experienced breastfeeding failure. Prolonged separation, lack of breastfeeding knowledge, inverted nipples, maternal anxiety, and depression were identified as independent risk factors. The nomogram model showed good predictive performance, with an AUC of 0.739 and positive net benefit across a wide range of threshold probabilities. This model could support targeted interventions in clinical practice.

African Journal of Reproductive HealthVol. 29(6)
Soochow University (CN), First Affiliated Hospital of Soochow University (CN)
Good health and well-being
Openalex Percentile: Top 78%
Breastfeeding Practices and Influences
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Risk factors and predictive modeling of exclusive breastfeeding failure in mothers separated from their infants — Xiangxue Wang, Weiwei Wu · African Journal of Reproductive Health (2025) | TGRS Research Map | TGRS