Sustained Molecular Allograft Injury After Episodes of Acute Rejection and Organizing Pneumonia Increases the Risk of Lung Allograft Failure
The degree of allograft injury on the molecular level after AR/OP events in lung transplant recipients is associated with the risk of developing CLAD or death. This study demonstrates the potential of dd-cfDNA for improving risk stratification and monitoring the resolution and treatment responses of lung allograft injury.
Authors
- Gerald J. Berry (ORCID: https://orcid.org/0000-0002-6176-2629)
- Hyesik Kong (ORCID: https://orcid.org/0000-0001-7540-2045)
- Ananth Charya (ORCID: https://orcid.org/0000-0002-9366-1515)
- Shambhu Aryal (ORCID: https://orcid.org/0000-0002-3753-4378)
- Xin Tian (ORCID: https://orcid.org/0000-0003-1896-2462)
- Steven D. Nathan (ORCID: https://orcid.org/0000-0002-6270-1617)
- Amy E. Lin (ORCID: https://orcid.org/0000-0002-0554-2832)
- Jonathan B. Orens
- Charles C. Marboe (ORCID: https://orcid.org/0000-0001-6844-209X)
- Sean Agbor-Enoh (ORCID: https://orcid.org/0000-0002-9380-9161)
- Ileana L. Ponor (ORCID: https://orcid.org/0000-0002-8258-4796)
- Moon Kyoo Jang (ORCID: https://orcid.org/0000-0002-1657-2877)
- Michael B. Keller
- Pali D. Shah
Institutions
- University of Maryland, Baltimore (US)
- National Institutes of Health (US)
- University of Maryland Medical Center (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
- Inova Fairfax Hospital (US)
- Johns Hopkins Bayview Medical Center (US)
- National Heart, Lung, and Blood Institute (US)
- Baltimore VA Medical Center (US)
- Digital Research Alliance of Canada
- Columbia University (US)
- Stanford University (US)
Publication Details
- Journal
- Transplantation Direct
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1097/txd.0000000000001828
- Citations
- 2
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 4.01