Clinical Implications and Application of Molecular Testing in the Diagnosis and Management of Thyroid Nodules in the Chinese Population
Molecular testing substantially improves diagnostic accuracy when integrated with cytology, facilitating the diagnosis of cytologically indeterminate nodules and offering prognostic insights for patients with thyroid cancer. See related commentary by Sehgal, p. 4869.
Authors
- Songtao Zhang (ORCID: https://orcid.org/0009-0002-9807-1263)
- Xingchen Li (ORCID: https://orcid.org/0009-0004-1117-2569)
- Rongli Xie (ORCID: https://orcid.org/0000-0002-5266-383X)
- Zeyu Wu (ORCID: https://orcid.org/0000-0002-1104-0839)
- Xiaoyue Zhang (ORCID: https://orcid.org/0009-0005-6161-6292)
- Feifei Ning (ORCID: https://orcid.org/0000-0002-7973-6509)
- Gaosong Wu
- Jianming Yuan (ORCID: https://orcid.org/0000-0003-3910-5339)
- Jian Chen (ORCID: https://orcid.org/0009-0005-6811-069X)
- Jian Fei (ORCID: https://orcid.org/0000-0001-6084-4211)
- Jiaqi Dai (ORCID: https://orcid.org/0000-0002-6457-5415)
- Min Ding (ORCID: https://orcid.org/0000-0001-5444-9397)
- Zhiqiang Yin (ORCID: https://orcid.org/0000-0002-0847-6535)
- Guohui Xiao (ORCID: https://orcid.org/0000-0001-9463-6955)
- Sanming Wang (ORCID: https://orcid.org/0009-0003-5745-5225)
- Rui Zhou (ORCID: https://orcid.org/0000-0003-0785-5258)
- Jiuzhou Zhao (ORCID: https://orcid.org/0000-0003-2711-3729)
Institutions
- Shanghai University of Engineering Science (CN)
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
- Wuhan University (CN)
- Zhengzhou University (CN)
- Shanghai CASB Biotechnology (China) (CN)
- Zhongnan Hospital of Wuhan University (CN)
- Shanghai Tenth People's Hospital (CN)
- State Key Laboratory of Oncogene and Related Genes (CN)
- Henan Cancer Hospital (CN)
- Guangdong Academy of Medical Sciences (CN)
- Community Health Center (US)
- Guangdong Provincial People's Hospital (CN)
- Shanghai Huangpu District Central Hospital (CN)
Publication Details
- Journal
- Clinical Cancer Research
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1158/1078-0432.ccr-25-0270
- Citations
- 2
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 3.63
Funders
- Shanghai Municipal Health Commission
- Natural Science Foundation of Guangdong Province
- Guangdong Provincial People's Hospital