Integrating network pharmacology and experimental verification to explore the protective effects of Evodia rutaecarpa in ischemic stroke
This study revealed the neuroprotective effects and molecular mechanisms of rutaecarpine on IS, providing a new theoretical basis for the clinical application of Evodia rutaecarpa.
Authors
- Hengjun Huang (ORCID: https://orcid.org/0000-0001-9842-9312)
- Zhixuan Huang
- Yangwen Ai
- Jian Li (ORCID: https://orcid.org/0000-0002-7521-8798)
- Hui Li (ORCID: https://orcid.org/0000-0003-2764-1142)
- Dongyue Zhou
Institutions
- Jiangxi University of Traditional Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China Academy of Chinese Medical Sciences (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-06-27
- DOI
- https://doi.org/10.1371/journal.pone.0327133
- Citations
- 1
- Primary Topic
- Multicomponent Synthesis of Heterocycles
- Type
- article
- Field-Weighted Citation Impact
- 0.94