The Effect of Metformin Usage in Patients With Metastatic Colorectal Cancer Receiving First-line Systemic Therapy

Metformin usage in patients with mCRC receiving systemic therapy may improve progression-free survival but does not significantly affect overall survival. This result outlines the potential of metformin in mCRC treatment, especially in enhancing the progression-free survival. Further studies are needed to confirm the role of metformin in systemic treatment of mCRC.

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Publication Details

Journal
In Vivo
Published
2025-06-27
DOI
https://doi.org/10.21873/invivo.14032
Primary Topic
Metabolism, Diabetes, and Cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

The Effect of Metformin Usage in Patients With Metastatic Colorectal Cancer Receiving First-line Systemic Therapy

Yasemin Geriş, Güngör Utkan, Merih Yalçıner, Efe Cem Erdat
In Vivo
Metabolism, Diabetes, and Cancer
article

The Effect of Metformin Usage in Patients With Metastatic Colorectal Cancer Receiving First-line Systemic Therapy

Yasemin Geriş, Güngör Utkan, Merih Yalçıner, Efe Cem Erdat
article en

Abstract

Metformin usage in patients with mCRC receiving systemic therapy may improve progression-free survival but does not significantly affect overall survival. This result outlines the potential of metformin in mCRC treatment, especially in enhancing the progression-free survival. Further studies are needed to confirm the role of metformin in systemic treatment of mCRC.

In VivoVol. 39(4)
Ankara University (TR)
Good health and well-being
Openalex Percentile: Top 86%
Metabolism, Diabetes, and Cancer
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