Pharmacokinetic Simulation of Optimal Lopinavir and Ritonavir Dose Combination for COVID-19: Boosting Lopinavir With Ritonavir
These findings provide a basis to quantify the booster effect of ritonavir on LPV in COVID-19 treatment and calculate the optimal LPV and ritonavir dose combination.
Authors
- Yoshikazu Matsuda
- Tomoji Maeda
- Ken-ichi Sako (ORCID: https://orcid.org/0000-0003-1486-5825)
- Yuta Nakamaru (ORCID: https://orcid.org/0009-0007-3485-0790)
- Naohito Ide (ORCID: https://orcid.org/0000-0002-0292-3672)
- Fumiyoshi Yamashita (ORCID: https://orcid.org/0000-0002-3503-8696)
Institutions
- Nihon Pharmaceutical University (JP)
- Kyoto University (JP)
- Kyoto Pharmaceutical University (JP)
Publication Details
- Journal
- In Vivo
- Published
- 2025-06-27
- DOI
- https://doi.org/10.21873/invivo.14005
- Primary Topic
- Pharmacological Effects and Toxicity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00