Microvascular Damage in the Deep Mucosal <i>Lamina Propria</i> Triggers the Onset of Colitis in Dextran Sulfate Sodium-induced Colitis in Mice
Early vascular impairment, particularly in the deep mucosal arteriolar plexus, precedes DSS-induced colitis in mice. Understanding these vascular disturbances may provide insights into pathogenesis of inflammatory bowel disease and aid in developing early detection and intervention strategies for UC in humans.
Authors
- Hisashi Hashimoto (ORCID: https://orcid.org/0000-0003-0089-9717)
- Moriaki Kusakabe (ORCID: https://orcid.org/0000-0001-6074-3728)
- Masataka Okabe (ORCID: https://orcid.org/0000-0002-8618-6859)
- Seiji Arihiro (ORCID: https://orcid.org/0000-0002-2008-1704)
- Hiroki Saijo
Institutions
- Jikei University School of Medicine (JP)
- The University of Tokyo (JP)
Publication Details
- Journal
- In Vivo
- Published
- 2025-06-27
- DOI
- https://doi.org/10.21873/invivo.13986
- Primary Topic
- Microscopic Colitis
- Type
- article
- Field-Weighted Citation Impact
- 0.00