Pneumonitis after chemoradiation followed by durvalumab for locally advanced lung cancer: predictors and effect on survival
PDP occurred in a third of patients resulting in treatment discontinuation in 14.3%. PDP grades 2-5 correlated with radiation dose to lungs V20 ≥ 27% and MHD ≥ 6 Gy. PDP was associated with inferior LC and PFS and trended for shorter OS.
Authors
- Jair Bar (ORCID: https://orcid.org/0000-0002-1224-3646)
- Hadas Sorotsky (ORCID: https://orcid.org/0000-0003-3310-970X)
- Akram Saad (ORCID: https://orcid.org/0000-0002-3803-4754)
- Lee Wilk
- Edith M. Marom (ORCID: https://orcid.org/0000-0002-5920-3967)
- Yaacov Richard Lawrence (ORCID: https://orcid.org/0000-0002-9959-2485)
- Amir Onn (ORCID: https://orcid.org/0000-0002-6602-0405)
- Sarit Appel (ORCID: https://orcid.org/0000-0002-4235-5075)
- Damien Urban
- G. Kalmanovitz
- Jeffery Goldstein
- Ori Haisraeli
Institutions
- Tel Aviv University (IL)
- Tel Aviv Sourasky Medical Center (IL)
- Sheba Medical Center (IL)
Publication Details
- Journal
- British Journal of Radiology
- Published
- 2025-06-18
- DOI
- https://doi.org/10.1093/bjr/tqaf133
- Citations
- 1
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 1.52