Two new polyacetylenes from the roots of <i>Dolomiaea souliei</i>

In this study, two new polyacetylenes were isolated from the extract portion with ethyl acetate from <i>Dolomiaea souliei</i> roots by implementing various chromatography techniques, such as the use of silica gel under normal-phase conditions, MPLC, molecular sieving utilising Sephadex LH-20, and purification through semi preparative HPLC. Their structures were elucidated as (<i>E</i>)-[(<i>Z</i>)-deca-8-en-4,6-diynyl]-3-(4-hydroxy-3-methoxyphenyl) acrylate (<b>1</b>) and 6 <i>R</i>-(4<i>E</i>, 12<i>E</i>)-tetradeca-4,12-dien-8,10-diyne-1,6-diyldiacetate (<b>2</b>) by multiple spectroscopic techniques such as 1D and 2D NMR, UV, IR, and HR ESI MS.

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Publication Details

Journal
Natural Product Research
Published
2025-06-27
DOI
https://doi.org/10.1080/14786419.2025.2525563
Primary Topic
Natural product bioactivities and synthesis
Type
article
Field-Weighted Citation Impact
0.00

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article

Two new polyacetylenes from the roots of Dolomiaea souliei

Min Chen, Zhihua Liao, Jiajia Liu, Ammara Khalid et al.
Natural Product Research
Natural product bioactivities and synthesis
article

Two new polyacetylenes from the roots of Dolomiaea souliei

Min Chen, Zhihua Liao, Jiajia Liu, Ammara Khalid, Fancheng Meng, Zhe Wang, Guowei Wang, Yu‐Ting Peng, Basma Refai
article en

Abstract

In this study, two new polyacetylenes were isolated from the extract portion with ethyl acetate from <i>Dolomiaea souliei</i> roots by implementing various chromatography techniques, such as the use of silica gel under normal-phase conditions, MPLC, molecular sieving utilising Sephadex LH-20, and purification through semi preparative HPLC. Their structures were elucidated as (<i>E</i>)-[(<i>Z</i>)-deca-8-en-4,6-diynyl]-3-(4-hydroxy-3-methoxyphenyl) acrylate (<b>1</b>) and 6 <i>R</i>-(4<i>E</i>, 12<i>E</i>)-tetradeca-4,12-dien-8,10-diyne-1,6-diyldiacetate (<b>2</b>) by multiple spectroscopic techniques such as 1D and 2D NMR, UV, IR, and HR ESI MS.

Natural Product Research
Southwest University (CN), Iqra University (PK)
National Natural Science Foundation of China, Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission, Fundamental Research Funds for the Central Universities, Open Research Fund of State Key Laboratory of Bioelectronics
Openalex Percentile: Top 86%
Natural product bioactivities and synthesis
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Two new polyacetylenes from the roots of <i>Dolomiaea souliei</i> — Min Chen, Zhihua Liao, et al. · Natural Product Research (2025) | TGRS Research Map | TGRS