A multi-view CNN model to predict resolving of new lung nodules on follow-up low-dose chest CT

Predicting the resolution of new intermediate lung nodules in lung cancer screening CT is a challenge. Our multi-view CNN model showed an AUC of 0.81, a specificity of 0.93, and a sensitivity of 0.63 at the nodule level. The multi-view model demonstrated a significant improvement in AUC compared to the three 2D models, one 2.5D model, and one 3D model.

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Publication Details

Journal
Insights into Imaging
Published
2025-06-27
DOI
https://doi.org/10.1186/s13244-025-02000-x
Citations
4
Primary Topic
Lung Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
6.07

Funders

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article

A multi-view CNN model to predict resolving of new lung nodules on follow-up low-dose chest CT

Marcel van Tuinen, Jingxuan Wang, Rozemarijn Vliegenthart, Peter M. A. van Ooijen et al.
4 citations
Insights into Imaging
Lung Cancer Diagnosis and Treatment
6.07
article

A multi-view CNN model to predict resolving of new lung nodules on follow-up low-dose chest CT

Marcel van Tuinen, Jingxuan Wang, Rozemarijn Vliegenthart, Peter M. A. van Ooijen, Xiaowen Zhang, Wei Tang
article en
4 citations

Abstract

Predicting the resolution of new intermediate lung nodules in lung cancer screening CT is a challenge. Our multi-view CNN model showed an AUC of 0.81, a specificity of 0.93, and a sensitivity of 0.63 at the nodule level. The multi-view model demonstrated a significant improvement in AUC compared to the three 2D models, one 2.5D model, and one 3D model.

Insights into ImagingVol. 16(1)
University Medical Center Groningen (NL), University of Groningen (NL)
Rijksuniversiteit Groningen, China Scholarship Council
Reduced inequalities, Peace, Justice and strong institutions
Openalex Percentile: Top 4%
Lung Cancer Diagnosis and Treatment
6.07
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A multi-view CNN model to predict resolving of new lung nodules on follow-up low-dose chest CT — Marcel van Tuinen, Jingxuan Wang, et al. · Insights into Imaging (2025) | TGRS Research Map | TGRS